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临床试验/NCT01386060
NCT01386060已完成不适用

Mindfulness Meditation in Chronic Stress: Measures of Adherence, Ability & Stress

Oregon Health and Science University2 个研究点 分布在 1 个国家目标入组 134 人开始时间: 2011年6月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
134
试验地点
2
主要终点
Changes in Physiological Markers of Stress

研究概览

简要总结

The study purpose is to evaluate efficacy of a mindfulness training intervention and learn about cognitive and physiological markers of stress.

详细描述

Subjects will first undergo a phone screening, and if eligible, they will complete three study visits at Week 1, Week 8, and Week 15. The study visits involve at-home surveys, voice recordings, physical measures (height, weight, waist-to-hip ratio, and blood pressure), EEG recordings (including recordings of electrodermal activity and heart rate variability), computer tasks, in-lab saliva collection, overnight urine collection, 2-day saliva collection at bed waking, 30 minutes post-waking, afternoon, and bedtime, and a small handheld device that randomly administers eight short assessments in the subjects' natural environment. Subjects will be randomized to receive a 6-week mindfulness meditation course either between the first and second study visits or between the second and third study visits. Participants who receive training during the first and second visits will continue meditating until the third visit. The one-on-one instruction occurs once a week for 1 ½ hours, and participants are asked to listen to guided meditations and do other mindfulness-based tasks on a daily basis between sessions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
50 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ages 50-85
  • Good General Health
  • Experiencing Stress
  • No current meditation practice
  • English speaking

排除标准

  • Cognitive Impairment
  • Neurological Disease
  • Major Untreated Depression

研究组 & 干预措施

Mindfulness Meditation Training

Experimental

Participants receive the 6-week meditation training intervention between the 1st and 2nd study visits.

干预措施: Mindfulness Meditation Training (Other)

Waitlist Control

No Intervention

Participants receive no intervention between the 1st and 2nd study visits. They receive the training between the 2nd and 3rd study visits only.

结局指标

主要结局

Changes in Physiological Markers of Stress

时间窗: Baseline (Week 1) and Visit 2 (Week 8)

Measure changes in blood pressure, heart rate, heart rate variability, neurological reaction time to visual stimuli, urine, saliva, waist-to-hip ratio, weight, and electrodermal response.

次要结局

  • Changes in self-reported measures of stress(Baseline (Week 1) and Visit 2 (Week 8))
  • Cognitive Changes(Baseline (Week 1) and Visit 2 (Week 8))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Barry S. Oken

MD

Oregon Health and Science University

研究点 (2)

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