Mindfulness Meditation in Chronic Stress: Measures of Adherence, Ability & Stress
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 134
- 试验地点
- 2
- 主要终点
- Changes in Physiological Markers of Stress
研究概览
简要总结
The study purpose is to evaluate efficacy of a mindfulness training intervention and learn about cognitive and physiological markers of stress.
详细描述
Subjects will first undergo a phone screening, and if eligible, they will complete three study visits at Week 1, Week 8, and Week 15. The study visits involve at-home surveys, voice recordings, physical measures (height, weight, waist-to-hip ratio, and blood pressure), EEG recordings (including recordings of electrodermal activity and heart rate variability), computer tasks, in-lab saliva collection, overnight urine collection, 2-day saliva collection at bed waking, 30 minutes post-waking, afternoon, and bedtime, and a small handheld device that randomly administers eight short assessments in the subjects' natural environment. Subjects will be randomized to receive a 6-week mindfulness meditation course either between the first and second study visits or between the second and third study visits. Participants who receive training during the first and second visits will continue meditating until the third visit. The one-on-one instruction occurs once a week for 1 ½ hours, and participants are asked to listen to guided meditations and do other mindfulness-based tasks on a daily basis between sessions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages 50-85
- •Good General Health
- •Experiencing Stress
- •No current meditation practice
- •English speaking
排除标准
- •Cognitive Impairment
- •Neurological Disease
- •Major Untreated Depression
研究组 & 干预措施
Mindfulness Meditation Training
Participants receive the 6-week meditation training intervention between the 1st and 2nd study visits.
干预措施: Mindfulness Meditation Training (Other)
Waitlist Control
Participants receive no intervention between the 1st and 2nd study visits. They receive the training between the 2nd and 3rd study visits only.
结局指标
主要结局
Changes in Physiological Markers of Stress
时间窗: Baseline (Week 1) and Visit 2 (Week 8)
Measure changes in blood pressure, heart rate, heart rate variability, neurological reaction time to visual stimuli, urine, saliva, waist-to-hip ratio, weight, and electrodermal response.
次要结局
- Changes in self-reported measures of stress(Baseline (Week 1) and Visit 2 (Week 8))
- Cognitive Changes(Baseline (Week 1) and Visit 2 (Week 8))
研究者
Barry S. Oken
MD
Oregon Health and Science University
