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Clinical Trials/NCT01386060
NCT01386060
Completed
Not Applicable

Mindfulness Meditation in Chronic Stress: Measures of Adherence, Ability & Stress

Oregon Health and Science University1 site in 1 country134 target enrollmentJune 2011
ConditionsAging

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aging
Sponsor
Oregon Health and Science University
Enrollment
134
Locations
1
Primary Endpoint
Changes in Physiological Markers of Stress
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The study purpose is to evaluate efficacy of a mindfulness training intervention and learn about cognitive and physiological markers of stress.

Detailed Description

Subjects will first undergo a phone screening, and if eligible, they will complete three study visits at Week 1, Week 8, and Week 15. The study visits involve at-home surveys, voice recordings, physical measures (height, weight, waist-to-hip ratio, and blood pressure), EEG recordings (including recordings of electrodermal activity and heart rate variability), computer tasks, in-lab saliva collection, overnight urine collection, 2-day saliva collection at bed waking, 30 minutes post-waking, afternoon, and bedtime, and a small handheld device that randomly administers eight short assessments in the subjects' natural environment. Subjects will be randomized to receive a 6-week mindfulness meditation course either between the first and second study visits or between the second and third study visits. Participants who receive training during the first and second visits will continue meditating until the third visit. The one-on-one instruction occurs once a week for 1 ½ hours, and participants are asked to listen to guided meditations and do other mindfulness-based tasks on a daily basis between sessions.

Registry
clinicaltrials.gov
Start Date
June 2011
End Date
June 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Barry S. Oken

MD

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

  • Ages 50-85
  • Good General Health
  • Experiencing Stress
  • No current meditation practice
  • English speaking

Exclusion Criteria

  • Cognitive Impairment
  • Neurological Disease
  • Major Untreated Depression

Outcomes

Primary Outcomes

Changes in Physiological Markers of Stress

Time Frame: Baseline (Week 1) and Visit 2 (Week 8)

Measure changes in blood pressure, heart rate, heart rate variability, neurological reaction time to visual stimuli, urine, saliva, waist-to-hip ratio, weight, and electrodermal response.

Secondary Outcomes

  • Changes in self-reported measures of stress(Baseline (Week 1) and Visit 2 (Week 8))
  • Cognitive Changes(Baseline (Week 1) and Visit 2 (Week 8))

Study Sites (1)

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