Phase II study of pre-operative chemoradiation using S-1 followed by surgical resection for potentially resectable and locally advanced pancreatic cancer
Phase 2
- Conditions
- Potentially resectable and locally advanced pancreatic cancer
- Registration Number
- JPRN-UMIN000003088
- Lead Sponsor
- Department of Surgery, Kansai Medical University Hirakataka Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients with other active cancers 2)Patients with watery diarrhea 3)Intractable pleural and pericardical effusion, or ascites 4)Severe co-morbid diseases 5)Pregnancy or insufficient contraception 6)Past history of severe drug-allergy 7)Active bacterial or viral infection 8)younger than 20 years old or older than 90 years old. 9)No written informed consent of the patients 10)Pregnancy or insufficient contraception 11)HIV infection 12)Doubtful understanding or contractual capacity of the patient 13)Patients seems inadequate for this study by investigator(s)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of histological curative resection or surgical curative resection
- Secondary Outcome Measures
Name Time Method Response rate of chemoradiation therapy Grading of histological response of chemoradiation therapy Safety of chemoradiation followed by surgical resection Operative mortality and morbidity