Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning

Not Applicable

Completed

• Conditions: Glucose Metabolism; Insulin
• Interventions: Dietary Supplement: Control; Dietary Supplement: High dairy protein; Dietary Supplement: High GI; Dietary Supplement: vegetable protein

• Registration Number: NCT01034241
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The purpose of this study is to determine whether different protein diets affects glucose and insulin metabolism and substrate partitioning.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-04
• Study First Submitted: 2009-12-16
• Study First Submitted QC: 2009-12-16
• Study First Posted: 2009-12-17
• Primary Completion: 2010-01
• Study Completion: 2010-03
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-21
• Last Update Posted: 2018-08-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• BMI: 18.5-25 kg/m2 (lean)
• Gender: Male
• Age: <35 years
• Caucasian

Exclusion Criteria

• Elevated fasting blood glucose level
• Lactose intolerant
• Diabetes Mellitus
• Hypertension (systolic/diastolic blood pressure)
• Hypotension (systolic/diastolic blood pressure)
• Cardiovascular diseases
• Asthma and other obstructive pulmonary diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control	Control	Diet consists of 15% dairy protein and low Glycemic Index (GI \< 40), 55 En% carbohydrates and 30 En% fat
High dairy protein	High dairy protein	Diet consists of 25% dairy protein and low GI (GI \< 40), 45 En% carbohydrates and 30 En% fat
High GI	High GI	Diet consists of 15 En% dairy protein and high GI(GI \> 60, 55 En% carbohydrates and 30 En% fat
vegetable protein	vegetable protein	Diet consists of 15 En% vegetable protein and low GI (GI \< 40), 55 En% carbohydrates and 30 En% fat

Primary Outcome Measures

Name	Time	Method
Glucose and insulin metabolism (24 h)	24 h

Secondary Outcome Measures

Name	Time	Method
Substrate partitioning and metabolic markers	24 h