A Comparison Between Two Types of Sealers in the Healing of Periapical Lesions
- Conditions
- Periapical Lesions
- Interventions
- Procedure: Root canal treatment with BioCeramic sealerProcedure: Root canal treatment with AH Plus sealer
- Registration Number
- NCT06400030
- Lead Sponsor
- Damascus University
- Brief Summary
This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions.
The study sample will consist of 41 patients with 65 teeth with clear periapical lesions.
Root canal obturation will be applied for all patients. BioCeramic sealer will be applied for the experimental group only.
The changes of the dimensions of the periapical lesion will be assessed using CBCT radiographs; pre- and post- treatment changes for each group will be evaluated individually.
- Detailed Description
Periapical lesions is considered as the most common symptoms associated with infected root canals.
Recently, the BioCeramic sealer has been considered one of the most common endodontic sealer that possess antibacterial properties, so it can have an effective role in the healing of periapical lesions, as well as its ability to prevent periapical leakage due to its attachment to the dentinal walls and gutta-percha cones.
This study will evaluate the effect of BioCeramic sealer on the healing of periapical lesions and the changes of the dimensions of the lesions.
Root canal obturation with gutta-percha cones will be applied in the two groups: The control group will receive the AH Plus with lateral condensation technique, and the experimental group will receive BioCeramic sealer with single cone technique.
CBCT radiographs will be gotten before and after one year of the treatment to evaluate the periapical lesion dimensions changes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 41
- One maxillary anterior tooth with a clear periapical lesion at least.
- Normal anatomic features and straight or slightly curved roots.
- The treated teeth must have complete roots and a closed apex.
- The ability to isolate the teeth with a rubber dam and restore them.
- Good oral hygiene.
- Good systemic health.
- Root caries.
- Root fractures or resorption.
- Signs of occlusal trauma on the treated tooth.
- Internal or external resorption.
- Active periodontal disease.
- Pregnancy or lactation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description BioCeramic Sealer Group (Experimental Group Root canal treatment with BioCeramic sealer in this group, root canal system was filled with BioCeramic-based sealer in conjunction with single gutta-percha cone. AH Plus sealer Group (Control Group) Root canal treatment with AH Plus sealer in this group, root canal system was filled with AH Plus sealer in conjunction with lateral condensation.
- Primary Outcome Measures
Name Time Method Change in the periapical lesion diameter before and after one year of the treatment (root canal obturation) This diameter of the periapical lesions is going to be measured on a CBCT image.
Initially, the sections of the periapical lesions will be evaluated in the three planes (sagittal, coronal, and axial). The section that contains the largest area of the lesion in each studied plane, will be used for measurement.
* If the shape of periapical lesion is circular, the periapical diameter would be taken (at this plane) relying on the scale in the program accompanying the radiograph (CBCT).
* If the shape of periapical lesion is not circular, the largest and smallest diameter of the lesion will be taken (at this plane) depending on the scale in the program accompanying the CBCT image, then the mean diameter will be calculated by collecting the previous two diameter and dividing them by 2.
Ultimately, the three diameters of the lesion (taken at the three planes) are collected and the total is divided into 3 to obtain the mean diameter of the lesion.
- Secondary Outcome Measures
Name Time Method Change in the presence of edema before, after six months, and one year of the treatment (root canal obturation) The detection of the edema will be performed using clinical examination (palpating the buccal tissues of the treated tooth).
Time Frame: before, after six months, and after one year of the treatment (root canal obturation)
Trial Locations
- Locations (1)
Damascus University
🇸🇾Damascus, Syrian Arab Republic