The Effect of Breastfeeding on the Development of Appendicitis in Adults

• Conditions: Appendicitis
• Interventions: Other: Breastfeeding

• Registration Number: NCT02679547
• Lead Sponsor: Sisli Hamidiye Etfal Training and Research Hospital

Brief Summary

Appendectomy is the most common emergent operative procedure performed worldwide. In this study investigators will investigate if there is a relationship between breast feeding and appendicitis in adults.

Detailed Description

Acute appendicitis accounts for the commonest indication for emergency visits during daily surgical practice. Breast feeding is very important both mother and the child. For the infant, breast feeding has an important role on the maturity of immune system. In the literature search, there are a little studies about the relationship between the breast feeding and appendicitis. In the literature, some studies suggests that the breast feeding may possibly give protection against the development of appendicitis. But the number of the patients and the control groups are limited. Because of that the investigators have planned to make this study with a lot of number of patients.

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-02-03
• Study First Submitted QC: 2016-02-09
• Study First Posted: 2016-02-10
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-16
• Last Update Posted: 2019-02-19
• Primary Completion: 2019-12
• Study Completion: 2020-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• Subjects has pathologically proven appendicitis for appendicitis group.

Exclusion Criteria

• Subjects has American Society of Anesthesiologists Physical Status classification 4,
• Subject has pregnancy,
• Subject has malignity,
• Subject has chronic illness,
• Subjects who won't accept to join the study
• Subjects who don't have family members

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control	Breastfeeding	The participants without appendicitis
Appendicitis	Breastfeeding	The patients with appendicitis

Primary Outcome Measures

Name	Time	Method
The breastfeeding status questionnaire in the appendicitis patients and participants without appendicitis	2 days	500 patients who have pathologically proven appendicitis and 1000 controls without appendicitis will be asked the question which is "How long did you had breast feeding?". The patients and the participants will be in the same age groups. Also the same question will be asked to at least one of the family member (mother, father, older brother or older sister). The breastfeeding status will be in three group ( 0-2 months, 2-6 months and \>6 months)

Trial Locations

Locations (5)

Sisli Etfal Training and Research Hospital; 🇹🇷 Istanbul, Turkey

Arnavutkoy State Hospital; 🇹🇷 Istanbul, Turkey

Istanbul Training and Research Hospital; 🇹🇷 Istanbul, Turkey

Bursa Yuksek Ihtisas Training and Research Hospital; 🇹🇷 Bursa, Turkey

Bezmialem Vakif University; 🇹🇷 Istanbul, Turkey