NCT05402566已完成不适用
MRI Assessment of Impaired Glucose Metabolism in Alzheimer's Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Deuterium Metabolic Imaging
研究概览
简要总结
Diseases of dementia are chronic, untreatable, and cause a massive burden of morbidity. In this proposal, we seek to tackle the problem of better, earlier, and more efficient diagnosis using deuterium metabolic imaging (DMI). The study is divided in two sub-studies: 1) optimization and simplification of DMI protocols, and 2) a cross-sectional study of DMI in Alzheimer's patients and healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Deuterium Metabolic Imaging
时间窗: Up to 150 mins after 2H-glucose ingestion
Lactate/glx ratio in the posterior cingulum (sub-study 2).
次要结局
- Deuterium Metabolic Imaging(Up to 150 mins after 2H-glucose ingestion)
- FDG-PET from the records (sub study 2)(At time of Deuterium Metabolic Imaging)
- Blood samples(Up to 150 mins after 2H-glucose ingestion)
- Cognitive tests from the records (sub study 2)(At time of Deuterium Metabolic Imaging)
- Cerebrospinal fluid biochemistry from the records (sub study 2)(At time of Deuterium Metabolic Imaging)
研究者
研究点 (1)
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