Incidence of augmented renal clearance and its effect on clinical outcomes of critically ill patients admitted in intensive care unit.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Incidence of early (on admission) or late (5th day) ARC in critically ill adult patients
研究概览
简要总结
Primary purpose of this study is to evaluate the incidence of augmented renal clearance in critically ill patients admitted in main ICU as incidence of ARC is seen mostly in trauma patients and maximum studies are done in trauma ICU.This study will help to know about the clinical outcomes in patients exhibiting ARC on admission (early) or ARC on fifth day (late) of admission. Apart from this we will study about the factors affecting ARC and multiple outcomes like duration of mechanical ventilation,inotrope requirement, length of stay and mortality in ICU.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •All adult patients admitted to the Main ICU
- •Without AKI
- •AKI with KDIGO stage 1 or 2 at presentation will be enrolled (as KDIGO 1 and 2 are rapidly reversible forms of AKI).
排除标准
- •Patients with ICU stay less than 24 hours.
- •Patients with chronic kidney disease, with or without RRT.
- •Patients with history of prolonged immobilization, obstetric patients, patients with evidence of rhabdomyolysis, AKI (KDIGO stage 3), patients who already received RRT prior to ICU admission.
结局指标
主要结局
Incidence of early (on admission) or late (5th day) ARC in critically ill adult patients
时间窗: On admission and 5th day.
次要结局
- 1. To correlate the CrCl measured using urine creatinine at 8-hour urine collection & serum creatinine with calculated CrCl using other methods:(Modified Cockgroft Gault formula, 4- variable Modification of Diet in Renal Disease (MDRD-4) equation & Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI).)
研究者
Meenakshi
Postgraduate Institute of Medical Education and Research,Chandigarh