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临床试验/CTRI/2025/07/091382
CTRI/2025/07/091382尚未招募不适用

Effect of Neural Tissue Mobilization on Hamstring length and pain in patients with prolapsed intervertebral disc

Sayani Das1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年8月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
active knee extension test

研究概览

简要总结

Background: A common spinal disorder that most commonly occurs in the lumbar region, prolapsed intervertebral disc disease (PIVD) is characterized by displacement of disc tissue beyond the intervertebral space.  Compression or irritation of adjacent nerve roots, most often the sciatic nerve, may cause low back pain, sciatica (pain traveling down the leg), and reduced lower limb flexibility, particularly of the hamstring muscles.

Individuals with lumbar disc disease tend to be tight in their hamstrings.  Both neural stress, which restricts the movement of the nerve itself, and defensive muscle guarding may be the reason.  Electrotherapy, core strengthening, traction, and flexibility training are typical elements of conventional PIVD rehabilitation; however, these interventions could not effectively deal with the mechanosensitivity of brain structures.

The objective of neural tissue mobilization, which is also referred to as neurodynamics or nerve gliding, is to restore peripheral nerves’ normal range of movement and flexibility.  Mobilizing the nerve through controlled joint and muscle movements along its course may reduce pain, improve range of motion, and reduce nerve irritation. Neural mobilization has been demonstrated in research to reduce symptoms in conditions like sciatica and carpal tunnel syndrome, but its application in the treatment of hamstring pain and stiffness related to PIVD is in its early stages.

Investigating the effectiveness of neural tissue mobilization in patients with PIVD may offer valuable information and lead to improved rehabilitation methods due to the relationship between neural structures, muscle flexibility, and pain..

**Purpose:**The purpose of this study is to evaluate the effectiveness of neural tissue mobilization in helping patients with prolapsed intervertebral disc disease (PIVD) extend their hamstring muscles and reduce their discomfort.

Methods: : A sample of PIVD with hamstring tightness will be recruited. Active knee extension test, finger to toe touch test for hamstring tightness and visual analogue scale for pain will be recorded at baseline. They will be divided into 2 groups: experimental group which receive the neural tissue mobilization and control group which receive conventional treatment . The treatment will be given for 5 days a week for 1 week and further assessments will be done at the end of 4 weeks.

Data Analysis:.: Data will be analyzed by using SPSS software version 24.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Diagnosis of Prolapsed Intervertebral Disc (PIVD): Confirmed by clinical assessment and imaging (e.g. MRI).
  • 2.Age Range: Typically, 18-60 years old (adults, to capture a general population while excluding extreme age-related factors).
  • 3.Presence of Hamstring Tightness: Active knee extension angle of less than 20° (indicating hamstring tightness or restriction).
  • 4.Pain Intensity: Moderate pain severity, typically between 3-7 on the Visual Analog Scale (VAS).
  • 5.Consent: Able to provide informed consent and willingness to participate in the study.
  • 6.No previous surgical intervention: No history of surgery related to the lumbar spine or hamstring muscles (unless stable post-surgery for a certain period).

排除标准

  • 1.Severe Neurological Deficits: Patients with significant motor weakness, sensory loss, or reflex abnormalities unrelated to PIVD.
  • 2.Severe Pain: Individuals with VAS score more than 8 or extreme pain that restricts participation in movement or exercise.
  • 3.Other Spinal Pathologies: Patients with conditions like spinal stenosis, spondylolisthesis, or vertebral fractures.
  • 4.Inflammatory Conditions: History of inflammatory diseases (e.g., rheumatoid arthritis or ankylosing spondylitis) that could affect mobility or pain perception.
  • 5.Pregnancy: Pregnant individuals, due to potential risks associated with certain manual therapy techniques.
  • 6.Recent Acute Injury: Hamstring injury or another acute injury within the past 6 weeks.
  • 7.Uncontrolled Systemic Conditions: Such as uncontrolled diabetes, cardiovascular conditions, or other conditions that contraindicate exercise or manual therapy.
  • 8.Psychiatric or Cognitive Issues: Individuals unable to follow study instructions or with cognitive impairments (e.g., severe dementia).

结局指标

主要结局

active knee extension test

时间窗: 5 days a week, 5 weeks

visual analogue scale

时间窗: 5 days a week, 5 weeks

次要结局

  • finger to toe touch test(5 days a week , 5 weeks)

研究者

发起方
Sayani Das
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Akanksha Saxena

Maharishi Markandeshwar (Deemed to be) University, MMIPR Mullana, Ambala, Haryana

研究点 (1)

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