Efficacy of Levamisol in Treating COVID-19

Phase 3

Completed

• Conditions: outpatient covid19 infected individuals.; COVID-19; U07.1

• Registration Number: IRCT20201124049480N1
• Lead Sponsor: Artesh University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 365

Inclusion Criteria

Age 18 years or older
Positive RT PCR test for COVID-19
Full consent and acceptance of the patient or his companion for taking the drug
Patient traceability
Women should not become pregnant for 30 days after the end of the study
patients should not take levamisole for five days before entering the study (because the half-life of ?the drug is 16 hours)

Exclusion Criteria

Another justifying cause (such as a bacterial or fungal infection) for the patient's symptoms
Allergic reaction to levamisole
Use of antibiotics other than those used to treat COVID-19
Shortness of breath due to cardiogenic pulmonary edema
Lactation
pregnancy
Patients with unstable hemodynamics;
History of cirrhosis, hepatitis, or severe liver disease,
GFR ?less than 30 ml/min
Patients receiving chemotherapy for cancer

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The general condition of the patient. Timepoint: Days 1,3,5,7,9,14. Method of measurement: Verbal Numeric Scale(VNS).

Secondary Outcome Measures

Name	Time	Method
Hospital admission. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Mortality rate. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Cough. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Sore throat. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Dyspnea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Myalgia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Diarrhea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Vomiting. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Nausea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Anosmia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Dysgeusia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Headache. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Fever. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.