Optimization of Ovarian Stimulation for Women with Endometrial Atypical Hyperplasia and Endometrial Cancer by Combination of Traditional Chinese and Western Medicine
- Conditions
- Endometrial Cancer and Endometrial Atypical Hyperplasia
- Registration Number
- ITMCTR2100004271
- Lead Sponsor
- Obstetrics and Gynecology Department, Peking University People's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
(1) Aged <= 40 years, women with a strong desire for childbearing;
(2) Women with endometrial atypical hyperplasia and endometrial cancer obtain remission after fertility sparing therapy;
(3) FIGO (2018 edition) staging: endometrial cancer IAG1-IAG2 Endometrial atypical hyperplasia;
(4) Imaging examination confirmed that the cancer was localized in the endometrium;
(5) Both estrogen receptor and progesterone receptor (ER, PR) were positive;
(6) Peripheral blood CA125 was normal;
(7) No severe fertility barriers after assessment of fertility ability;
(8) Women sign informed consent and have better follow-up conditions.
(1) Women with serious diseases or severe impairment of liver and kidney function;
(2) Women with endometrioid adenocarcinoma whose pathological stage or grade is higher than that of stage Ia and G2, or those with deep myometrial invasion, cervical invasion, or metastasized to pelvic and abdominal cavity;
(3) Women with other types of endometrial cancer or other malignant tumors of the reproductive system;
(4) Chronic diseases which are not suitable for pregnancy.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ive birth rate;
- Secondary Outcome Measures
Name Time Method Clinical pregnancy rate;Ovarian reserve;