MedPath

Skills for adolescent wellbeing

Not Applicable
Conditions
Prevention of depression in young people at increased risk for depression
Mental and Behavioural Disorders
Registration Number
ISRCTN13924193
Lead Sponsor
Cardiff University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Ongoing
Sex
All
Target Recruitment
400
Inclusion Criteria

Current inclusion criteria as of 22/08/2024:

1. Adolescents aged 13-19 years at study entry
2. Experiencing subthreshold depressive symptoms (CES-D score >=16) , and/or has a history of depression according to DSM-5.
3. Living with a parent (biological or non-biological) who has a history of recurrent unipolar depression (at least 1 previous episodes) who is willing and able to engage with a depression treatment plan
4. Both young person and parent have access to the internet via a desktop/laptop/phone/tablet and have a valid email address or mobile phone number
5. Both young person and parent have the ability to complete trial activities as specified in the protocol, e.g., sufficient understanding of English language, absence of learning disability that would impair ability to participate, and for the young person, ability to participate in small group therapy sessions

______

Previous inclusion criteria:

1. Adolescents aged 13-17 years at study entry
2. Experiencing subthreshold depressive symptoms (CES-D score >=20) , and/or has a history of depression according to DSM-5.
3. Living with a parent (biological or non-biological) who has a history of recurrent unipolar depression (at least 2 previous episodes) who is willing and able to engage with a depression treatment plan
4. Both young person and parent have access to the internet via a desktop/laptop/phone/tablet and have a valid email address or mobile phone number
5. Both young person and parent have the ability to complete trial activities as specified in the protocol, e.g., sufficient understanding of English language, absence of learning disability that would impair ability to participate, and for the young person, ability to participate in small group therapy sessions

Exclusion Criteria

Current exclusion criteria as of 22/08/2024:

1. Young person already receiving specialist treatment for depression (e.g. currently on antidepressants, or is currently receiving cognitive behavioural therapy (CBT))
2. Young person has a current diagnosis of depression as given by a doctor or healthcare professional
3. Young person has been told by a doctor or healthcare professional that they have a primary diagnosis of bipolar disorder, schizophrenia, eating disorder or alcohol/drug dependence or have generalized learning difficulties, that the parent judges would prevent them from participating in trial activities
4. Parent has been told by a doctor or healthcare professional that they have a diagnosis of bipolar disorder, schizophrenia or personality disorder
5. Parent is receiving treatment from secondary mental health services (e.g. community mental health team or psychiatrist)
6. Parent or young person are not resident in the UK

_____

Previous exclusion criteria as of 01/03/2024:

1. Young person already receiving specialist treatment for depression (e.g. currently on antidepressants, or has received a full course of cognitive behavioural therapy (CBT) previously)
2. Young person is experiencing a current depression episode at baseline that meets DSM-5 diagnostic criteria (i.e. five or more symptoms including either depressed mood/irritable mood and loss of interest that are present during the same 2-week period and represent a change from previous functioning)
3. Young person has been told by a doctor or healthcare professional that they have a primary diagnosis of bipolar disorder, schizophrenia, eating disorder or alcohol/drug dependence or have generalized learning difficulties, that the parent judges would prevent them from participating in trial activities
4. Parent has been told by a doctor or healthcare professional that they have a diagnosis of bipolar disorder, schizophrenia or personality disorder
5. Parent is receiving treatment from secondary mental health services (e.g. community mental health team or psychiatrist)
6. Parent or young person are not resident in the UK

_____

Previous exclusion criteria:

1. Young person already receiving specialist treatment for depression (e.g. currently on antidepressants, or has received a full course of cognitive behavioural therapy (CBT) previously)
2. Young person is experiencing a current depression episode at baseline that meets DSM-5 diagnostic criteria (i.e. five or more symptoms including either depressed mood/irritable mood and loss of interest that are present during the same 2-week period and represent a change from previous functioning)
3. Young person has been told by a doctor or healthcare professional that they have a primary diagnosis of bipolar disorder, schizophrenia, eating disorder or alcohol/drug dependence or have generalized learning difficulties, that the parent judges would prevent them from participating in trial activities
4. Parent has been told by a doctor or healthcare professional that they have a diagnosis of bipolar disorder, schizophrenia, personality disorder or post-traumatic stress disorder
5. Parent is receiving treatment from secondary mental health services (e.g. community mental health team or psychiatrist)
6. Parent or young person are not resident in the UK

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time to a DSM-5 major depressive episode occurring in the young person during the 9 month follow up period (measured using the young person and parent rated Longitudinal Interview Follow-up Evaluation (LIFE) at 9 months)
Secondary Outcome Measures
NameTimeMethod
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