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Clinical Trials/NCT04437784
NCT04437784
Completed
Not Applicable

Laparoscopic Versus Open Mesh Repair of Bilateral Primary Inguinal Hernia; 3 Armed Randomized Study

Alexandria University0 sites180 target enrollmentJune 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bilateral Inguinal Hernia
Sponsor
Alexandria University
Enrollment
180
Primary Endpoint
Operative time
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The best approach for simultaneous repair of bilateral inguinal hernia is controversial. The aim of this study is to compare the outcomes after laparoscopic versus open mesh repair of bilateral primary inguinal hernia

Detailed Description

This prospective study included 180 patients with bilateral primary inguinal hernia; randomized by sealed envelopes into 3 groups; each includes 60 patients. Group I treated by laparoscopic trans-abdominal pre-peritoneal (TAPP) repair using 2 separate meshes, Group II treated by open pre-peritoneal (PP) single mesh repair, while Group III treated by bilateral Lichtenstein repair. The 3 groups were compared regarding: operative time, postoperative complications, postoperative pain, 3 years-recurrence rate and patient's satisfaction. .

Registry
clinicaltrials.gov
Start Date
June 2014
End Date
June 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohamed El Messiry

Assistant professor of Surgery

Alexandria University

Eligibility Criteria

Inclusion Criteria

  • Patients with painless uncomplicated primary bilateral inguinal hernias

Exclusion Criteria

  • Immune compromised patients
  • Coagulopathy
  • Chronic liver or renal disease
  • High-risk patients unfit for major surgery (ASA III or IV),
  • Massive scrotal hernias, Recurrent or Complicated hernias
  • Groin pain due to any other pathology
  • Previous infra-umbilical surgery

Outcomes

Primary Outcomes

Operative time

Time Frame: From skin incision until incision closure at the end of surgery

Operative time (in minutes)

Postoperative pain after 7 days

Time Frame: 7 days after surgery

Pain intensity was assessed 7 days after surgery using the pain visual analogue scale (VAS) with values ranging from 1 (no pain) to 10 (worst possible pain)

Early postoperative complications

Time Frame: Within 30 days after the surgery

All complication related to surgery developed within 30 days after the surgery

Postoperative pain after 24 hours

Time Frame: 24 hours after surgery

Pain intensity was assessed 24 hours after surgery using the pain visual analogue scale (VAS) with values ranging from 1 (no pain) to 10 (worst possible pain)

Secondary Outcomes

  • 3 years hernia recurrence rate(within 3 years after surgery)
  • Patient's satisfaction score(within 3 years after surgery)
  • Chronic Groin pain(After 3 months postoperatively)

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