Assessment and Treatment Patients With Atypical Facial Pain Trough Repetitive Transcranial Magnetic Stimulation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Change in Baselin of Pain
研究概览
简要总结
Atypical Facial Pain is a chronic condition and presents controversies during diagnostic and treatment, between specialist not have consensus about the pathophysiology. It is possible consider this entitie a potential neuropathic cause without pathological signs. It knows the repetitive transcranial magnetic presents good results in the treatment of chronic pain coditions. The aim this study is evaluated the thresholds and excitability cortical in patients with AFP and verify the patterns of improvement in pain for patients undergoing rTMS compared to controls, as well as the therapeutic response to neuromodulation procedures. This enroll 20 patients with DAF and 20 controls treated with rTMS (5 sessions) and evaluated through questionnaires (EDOF clinical record, McGill Pain Questionnaire, Visual Analogue Scale, Inventory of symptoms of neuropathic pain, neuropathic pain DN4 questionnaire, SF -36, brief pain inventory). At the end of the data will be statistically analyzed and expressed as mean and standard deviation, and analyzed by Student's t test, analysis of variance (ANOVA), Tukey-Kramer and Pearson correlation. The level of significance is 5%. The results will be published in journals indexed in the area both nationally and internationally and presented at conferences and scientific meetings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Fulfill criteria of Atypical Facial Pain by International Headache Society
- •Signed Term of Informed Consent
排除标准
- •Trauma of Skull, epilepsy don't treated,
- •Use of medications decrease the seizure threshold
- •Patients in use of drugs, how cocaine and alcohol
- •neurosurgical clips, pacemakers, increased intracranial pressure (risk of sequelae after seizure)
- •Pregnant or lacting women
结局指标
主要结局
Change in Baselin of Pain
时间窗: base line (moment of inclusion) and end of each session rTMS (4X in three months)
Assessing by verbal analog scale (VAS)
次要结局
- Excitability cortical(baseline (in the moment of inclusion) and end of each session of rTMS (4X in three months))
研究者
Ricardo Galhardoni
PhD student
University of Sao Paulo
