Clinical relevance of cardiotomy blood salvage during cardiopulmonary bypass

Completed

• Conditions: Coronary Artery Disease - Cardiopulmonary bypass; Circulatory System; Chronic ischaemic heart disease

• Registration Number: ISRCTN87590585
• Lead Sponsor: niversity of Ottawa Heart Institute (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 274

Inclusion Criteria

1. Adult patients scheduled for coronary artery bypass grafting requiring CPB
2. Aged greater than or equal to 18 years old, either sex

Exclusion Criteria

1. Emergency surgery
2. Patients unable to undergo cognitive testing (visual or motor problems, unable to speak English or French)
3. Undergoing reoperative surgery
4. Patients undergoing non-CABG procedures or other cardiac procedures in addition to CABG
5. Patients with preoperative coagulopathy, bleeding diathesis or thrombocytopenia (less than 140,000 /µl)
6. Patients with renal insufficiency (creatinine 2 x normal) or hepatic insufficiency (elevated liver function tests, elevated baseline international normalised ratio [INR])
7. Mini-Mental State Examination (MMSE) less than 24/30 at pre-operative visit

Study & Design

• Study Type: Interventional
• Study Design: Not specified