The Relation Between Thyroid , Parathyroid Hormones and Estimated Glomerular Filtration Rate in Chronic Kidney Disease Patients in Assiut
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 主要终点
- The Relation between thyroid , parathyroid hormones and estimated glomerular filtration rate in chronic kidney disease patients in Assiut
研究概览
简要总结
To evaluate the relation between thyroid, parathyroid hormones and estimated glomerular filtration rate in chronic kidney disease .
详细描述
CKD is defined as abnormalities of kidney structure or function, present for >3 months, with implications for health. CKD is classified based on Cause, GFR category (G1-G5), and Albuminuria category (A1-A3) .
The global prevalence of CKD is 13.4%, with 10.6% being stages 3-5 ,Over the past 10 years, the death rate due to CKD has increased by 31.7% .
CKD patients remain sometimes asymptomatic, presenting the complications typical of renal dysfunction only in more advanced stages. Its treatment can be conservative usually in patients with glomerular filtration rate above 15 ml/minute without indications of dialysis or replacement therapy .
In CKD patients the changes of endocrine system levels may arise from several causes as the kidney is the site of degradation & synthesis of many different hormones .
So thyroid and parathyroid hormones dysfunction has been recognized as common co-morbidity that is often diagnosed with CKD .
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CKD patients
- •Age (18-80 years)
- •Diabetic nephropathy
- •Hypertensive nephropathy
- •Chronic pyelonephritis
- •Obstructive nephropathy
- •Polycystic kidney
- •Gout nephropathy
- •Nephrosclerosis
排除标准
- •Patients underage of 18 and above 80
- •Patients with history of thyroidectomy and parathyroidectomy
- •Patients with history of thyroid and parathyroid disease before diagnosis of CKD
结局指标
主要结局
The Relation between thyroid , parathyroid hormones and estimated glomerular filtration rate in chronic kidney disease patients in Assiut
时间窗: Baseline
To evaluate the relation between thyroid, parathyroid hormones and estimated glomerular filtration rate in chronic kidney disease different stages
次要结局
未报告次要终点
研究者
Sara Magdy Ahmed Mohammed
Resident doctor
Assiut University