Randomised controlled trial on the effects of parenteral fish oil emulsion in patients with severe acute pancreatitis - Effects of fish oil emulsion on severe acute pancreatitis patients

niversity Hospitals of leicester NHS Trust0 个研究点目标入组 44 人开始时间: 2010年3月18日最近更新: 2020年6月22日

适应症

试验速览

暂无简介。

•All conscious patients between age of 18-85 admitted to the Leicester General hospital with severe acute pancreatitis proven by:
•a) compatible clinical features (abdominal pain with or without vomiting);
•b) associated with elevated serum amylase levels (>or=to 3 times the normal values) i,e >900 iu/l); and
•c) one of the severity criteria as outlined in the Atlanata severity criteria.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•The following will be excluded from the study:
•Patients unconscious or unable to consent for themselves.
•Patients below the age of 18 or above 85 years old.
•Hypersensitivity to fish, egg or soy protein or other active substances of the TPN.
•Uncontrolled hyperlipidaemia
•Severe primary blood coagulation disorder
•Acute pancreatitis accompanied with hyperlipidaemia
•Ketoacidosis
•Acute thromboembolic disease
•Severe liver failure
•Acute phase of myocardial infarction or stroke
•Pregnancy and lactation
•Severe renal failure without access to haemofiltration or dialysis (all patients with renal failure in Leicester General Hospital will have access to haemofiltration or dialysis if clinically indicated and needed)

发起方

niversity Hospitals of leicester NHS Trust