NCT00171743已完成4 期
Switch From Tacrolimus to Cyclosporine Microemulsion: Immunosuppressive Agents and Diabetes Management in Liver Transplant Recipients in Maintenance (DIALIVER)
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Novartis
- 入组人数
- 47
研究概览
简要总结
The purpose of this study is to determine whether the switch from tacrolimus to cyclosporine microemulsion benefits post-transplant diabetes management (in terms of glycogenic control and insulin dosage) in stable liver transplant recipients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least 4 months post-transplant
- •Patients in treatment with tacrolimus
- •Post-transplant diabetes treated with insulin for at least one month
排除标准
- •Known hypersensitivity to cyclosporine microemulsion
- •Investigational drug within 60 days before baseline or during the study
- •Patients who cannot comply with the study requirements
- •Other protocol-defined exclusion criteria applied
研究者
相似试验
Unknown
4 期
The Effects of Conversion From Cyclosporine to Tacrolimus on the Changes of Cardiovascular Risk Profiles and Serum Metabolites in Renal Transplant RecipientsCYCLOSPORINE/TACROLIMUSNCT02496494Kyungpook National University Hospital50
尚未招募
不适用
Conversion from cyclosporine to tacrolimus followed by randomized C0 or C4 Bayesian monitoring stable liver transplant patients.kidney fuction in livertransplantation patientsNL-OMON22214MD. PhD. B. van Hoek50
已完成
4 期
Evaluation of Cyclosporine Microemulsion and Tacrolimus on the Rate of New Onset Diabetes Mellitus in Kidney Transplantation RecipientsKidney TransplantNCT00171496Novartis693
进行中（未招募）
不适用
Conversion from cyclosporine to tacrolimus followed by randomized C0 or Bayesian monitoring using the C4 timepoint The effect on kidney function - FK04-studyEffect of immunosuppressive medication on renal function following livertransplantationMedDRA version: 9.1Level: LLTClassification code 10024716Term: Liver transplantationEUCTR2008-000627-26-NLeiden University Medical Center50
已完成
不适用
conversion from cyclosporine to tacrolimus followed by randomized C0 or Bayesian monitoring using the C4 time point . The effect on kidney function.Livertransplantantion patients10019654NL-OMON31971eids Universitair Medisch Centrum50