ISRCTN11824145
Completed
Not Applicable
A Randomised Trial of Two Chemotherapy Regimens in the Treatment of Operable Osteosarcoma (Doxorubicin-Cisplatin versus Methotrexate-Vincristine-Doxorubicin plus Doxorubicin-Cisplatin plus Bleomycin-Cyclophosphamide-Dactinomycin)
Medical Research Council (MRC) (UK)0 sites400 target enrollmentAugust 19, 2002
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bone cancer
- Sponsor
- Medical Research Council (MRC) (UK)
- Enrollment
- 400
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged \<40 years
- •2\. Biopsy proven osteosarcoma
- •3\. Non\-metastatic, untreated osteosarcoma of the long bones of an extremity
- •4\. Normal cardiac, renal, hepatic, hematologic and pulmonary function prior to entry
- •5\. Patients with parosteal, periosteal, pagetoid and post irradiation sarcoma or who have an inoperable tumour are excluded
- •6\. No previous chemotherapy
- •7\. No previous radiotherapy to the primary tumour
- •8\. No medical contraindications to treatment
Exclusion Criteria
- •Not provided at time of registration.
Outcomes
Primary Outcomes
Not specified
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