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临床试验/NCT07306377
NCT07306377已完成不适用

Helicobacter Pylori Infection as A Potential Risk Factor for Dyslipidemia: Insights From Atherogenic Index of Plasma (AIP)

Tanta University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2025年1月2日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
300
试验地点
1
主要终点
Atherogenic Index of Plasma (AIP)

研究概览

简要总结

Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are important for heart health. Changes in lipid levels, such as higher triglycerides and lower "good" cholesterol (HDL), can increase the risk of cardiovascular disease.

This study will examine whether H. pylori infection is linked to changes in lipid profiles, especially the Atherogenic Index of Plasma (AIP). AIP is a calculation based on triglycerides and HDL cholesterol that helps predict the risk of heart disease.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients older than 18 years.
  • Able to sign the written consent.
  • Willing to participate in the research and undergo H. pylori testing. Exclusion criteria
  • Unwilling to participate in the study.
  • History of severe metabolic disorders.
  • Taking medications that affect adipose tissue metabolism.
  • History of gastric surgery.

排除标准

  • 未提供

结局指标

主要结局

Atherogenic Index of Plasma (AIP)

时间窗: Baseline (single fasting blood sample at enrollment).

AIP is calculated as log10(triglycerides/HDL cholesterol).

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nahla Ahmed Khalaf

Lecturer of Tropical Medicine and Infectious Diseases

Tanta University

研究点 (1)

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