Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cystic Fibrosis
- Sponsor
- Bezmialem Vakif University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- M. Quadriceps strength
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The effect of comprehensive respiratory physiotherapy applications on respiratory function, functional capacity and peripheral muscle strength in children with cystic fibrosis and non-cystic fibrosis will be compared.
Detailed Description
Bronchiectasis may be a congenital cause such as cystic fibrosis (CF) or non-cystic fibrosis such as primary ciliary dyskinesia, post-infectious conditions, aspiration and immunodeficiency; It is a disease characterized by irreversible dilatation of airways. Symptoms; purulent sputum production, chronic cough, hemoptysis, recurrent fever and pleurisy. Mucociliary clearance disorder secondary to inflammation and involvement of exocrine glands in CF plays a major role in the development of symptoms; In non-cystic fibrosis bronchiectasis (NCFB), the development of similar symptoms may occur regardless of these reasons. However, in the examinations of CF, proximal airways; In NCFB, distal airways have been affected more intensively. As part of pulmonary rehabilitation, comprehensive respiratory physiotherapy (CRP) has an important role in the treatment and management of bronchiectasis. Airway cleaning techniques, approaches to reducing respiratory work, and patient education form the basis of CRP and play an active role in the treatment and management of the disease. In the literature, there are studies in which the effects of CRP are given in both CF and NCFB patients and studies comparing evaluation results in both groups without treatment. However, no study was found to compare the efficacy of CRP in these two groups of diseases. Therefore, in this study, the investigators aimed to investigate the differences between the efficacy of CRP among the groups in children with CF and NCFB.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Being between 6-18 years old
- •Clinically diagnosed as cystic fibrosis or non-cystic fibrosis bronchiectasis
Exclusion Criteria
- •Previous history of lung or liver transplantation
- •Have had an acute exacerbation in the last month and / or have a history of hospitalization
- •Having a diagnosis of orthopedic problems affecting mobility or a history of musculoskelatal surgery
Outcomes
Primary Outcomes
M. Quadriceps strength
Time Frame: 8 Weeks
sometric M. Quadriceps strength (kg) will be measured using electronic hand held dynamometer in sitting position.
Peak Expiratory Flow (PEF)
Time Frame: 8 Weeks
PEF will be measured using basic spirometry and expressed as the percentage of the predicted value according to the guideline of European Respiratory Society (ERS)
Respiratory Muscle Strength - MEP
Time Frame: 8 Weeks
Maximum Expiratory Pressure (MEP) will be measured using MicroRPM portable manometer and the unit will be expressed in mmHg
Six-minute walk test distance
Time Frame: 8 Weeks
Distance walked in six minutes will be recorded in meters. Test will be conducted according to the guideline of American Thoracic Society (ATS)
Forced Vital Capacity (FVC)
Time Frame: 8 Weeks
FVC will be measured using basic spirometry and expressed as the percentage of the predicted value according to the guideline of European Respiratory Society (ERS)
Respiratory Muscle Strength - MIP
Time Frame: 8 Weeks
Maximum Inspiratory Pressure (MIP) will be measured using MicroRPM portable manometer and the unit will be expressed in mmHg
Forced Expiratory Volume in 1 second (FEV1)
Time Frame: 8 Weeks
FEV1 will be measured using basic spirometry and expressed as the percentage of the predicted value according to the guideline of European Respiratory Society (ERS)