A placebo-controlled clinical trial to assess efficacy of tranexamic acid in reducing hemorrhage after vaginal delivery
Phase 2
- Conditions
- postpartum hemorrhage.Haemorrhage following delivery of placenta
- Registration Number
- IRCT201204079399N1
- Lead Sponsor
- Vice chancellor for research ,Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 200
Inclusion Criteria
1- inclusion criteria:
- women with term, singleton pregnancy candidate for the first vaginal delivery
-No history of sever medical complications involving the heart,brain ,kidney
- No history of allergy to tranexamic acid
-No history of visual problem
-No history of sever pregnancy complications such as preeclampsia
-No history of thromboembolic events
2- exclusion criteria:
-patient avoidance
-placenta abruption
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin. Timepoint: Before and 24 hours after delivery. Method of measurement: laboratory.;Maternal death. Timepoint: During 24 hours after delivery. Method of measurement: outcome form.
- Secondary Outcome Measures
Name Time Method Blood transfusion. Timepoint: 24 hours after delivery. Method of measurement: outcome form.;Thromboembolic events in mother. Timepoint: 24 hours after delivery. Method of measurement: physical exam.;Surgical intervention. Timepoint: 24 hours after delivery. Method of measurement: outcome form.