Effects of herbal medicine for dysmenorrhea treatment on accompanied acne vulgaris: double-blind, randomized, parallel-group, multi-center trial

Kyung Hee University Oriental Medical Center0 个研究点目标入组 116 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•1. Women aged over 19 years and in childbearing age
•2. Patients who have more than 10 inflammatory acne lesion on their face
•3. Patients who have menstrual pain more than grade 1 according to the verbal multidimensional scoring system
•4. Patients who have regular menstrual cycle from 23 days to 33 days within 3 months
•5. Patients who deteriorate acne vulgaris related to the menstrual cycle
•6. Patients who don’t have any problems for expressing their thoughts
•7. Written informed consent

•1. Patients who taken following medicine
•? Topical or systemic corticosteroids (within 1 month)
•? Herbal medicine for acne treatment (within 1 month)
•? Nonsteroidal antiinflammatory drugs (NSAIDs) (within 2 weeks)
•? Oral contraceptives (within 1 month)
•? Topical or oral vitamin A derivatives (within 1 month)
•? Antibiotics (within 1 month)
•? Other unstable drugs as judged by the investigators
•2. Body Mass Index (BMI) <19 or BMI = 25
•3. Liver function abnormality (Aspartate aminotransferase (AST) or alanine aminotransferase (ALT)=60IU/L) or renal function abnormality (blood urea nitrogen (BUN)=30mg/dL or a serum creatinine levels = 1.5mg/dL)
•4. Pregnancy or breastfeeding or having plan to be pregnant or having possibility for pregnancy
•5. Patients who have malignant tumor, serious infection or severe systemic diseases
•6. Patients who attended to other clinical trials during previous 3 months
•7. unsuitability as judged by the investigators

发起方

Kyung Hee University Oriental Medical Center