The effect of oxytocin and vasopressin in reducing laparoscopic myomectomy bleeding in wome
Phase 3
Recruiting
- Conditions
- Bleeding during surgery.
- Registration Number
- IRCT20150817023666N15
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Age of 20 to 45 years
Symptomatic uterine fibroids candidate for laparoscopic surgery
No response to drug treatment
Exclusion Criteria
Underlying diseases related to blood factors
Pregnancy
Women who are candidates for hysterectomy
People for whom anesthesia is harmful
A history of an adverse reaction or allergy to vasopressin, and an active cardiovascular or pulmonary disease that indicates a problem with vasopressin use.
Long QT interval
Leiomyoma located in the area of the uterus that connects to the arteries or ligaments of the uterus or cervix and is difficult to remove without hysterectomy.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding during surgery. Timepoint: The volume of suctioned blood is measured during the operation, after surgery and 12 hours after the operation. Method of measurement: Measurement of blood hemoglobin.
- Secondary Outcome Measures
Name Time Method Duration of surgery. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Duration of hospitalization. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Postoperative side effects such as allergies. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Cardiovascular disorders. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Pulmonary edema. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Fever. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).;Infection. Timepoint: Before and after surgery and 12 hours after surgery. Method of measurement: Patient's file (document).