Immunity and Nasal Fungal Colonization
Completed
- Conditions
- Colonization, Asymptomatic
- Interventions
- Other: nasal irrigation
- Registration Number
- NCT05231499
- Lead Sponsor
- Taichung Veterans General Hospital
- Brief Summary
Fungal colonization causes opportunistic infection that may manifest when the host's immune status deteriorates. The purpose of this study was to determine the prevalence of fungal colonization in immunocompromised subjects compared to healthy controls.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
- Immunocompromised subjects included those who had known risk factors for fungal infection, including malignant diseases, diabetes, autoimmune disorders, renal or hepatic insufficiency, organ transplantation, or use of immunosuppressants
- Healthy volunteers had neither sinonasal symptoms nor nasal endoscopic inflammation.
Exclusion Criteria
- Patients were excluded if they were under 20 years old, were receiving antifungal medication, or were pregnant.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description immunocompromised subjects nasal irrigation -
- Primary Outcome Measures
Name Time Method nasal lavage pooled fungal microbiota 1 month
- Secondary Outcome Measures
Name Time Method nasal lavage aspergillus qPCR 1 month
Trial Locations
- Locations (1)
Department of Otolaryngology, Taichung Veterans General Hospital
🇨🇳Taichang, Taiwan