NCT05231499已完成不适用
Host Immunity and Nasal Fungal Colonization
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- nasal lavage pooled fungal microbiota
研究概览
简要总结
Fungal colonization causes opportunistic infection that may manifest when the host's immune status deteriorates. The purpose of this study was to determine the prevalence of fungal colonization in immunocompromised subjects compared to healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Immunocompromised subjects included those who had known risk factors for fungal infection, including malignant diseases, diabetes, autoimmune disorders, renal or hepatic insufficiency, organ transplantation, or use of immunosuppressants
- •Healthy volunteers had neither sinonasal symptoms nor nasal endoscopic inflammation.
排除标准
- •Patients were excluded if they were under 20 years old, were receiving antifungal medication, or were pregnant.
结局指标
主要结局
nasal lavage pooled fungal microbiota
时间窗: 1 month
次要结局
- nasal lavage aspergillus qPCR(1 month)
研究者
研究点 (1)
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