Experimental measurement of analgesia during anesthesia
- Conditions
- Intraoperative measurement nociception analgesia levelIn het NL:pijnmeting intraoperatief nociceptie pijnstilling
- Registration Number
- NL-OMON24176
- Lead Sponsor
- MC
- Brief Summary
Treister R et al. Differentiating between heat pain intensities: The combined effect of multiple autonomic parameters. Pain. 2012 May 28. 2. Edry R et al. Non‐Linear multi‐parameter approach for evaluation of nociception level during general anesthesia, Proc Conf American Soc of Anes Conf, Oct 2012. 3. Ben-Israel N, Kliger M, Zuckerman G, Katz Y, Edry R. Monitoring the nociception level: a multi-parameter approach. J Clin Monit Comput. 2013 Dec;27(6):659-68.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Age: 18‐80 years;
Sex: male or female;
Surgery: Any surgery under general anesthesia;
ASA status: 1, 2 or 3.
Age: < 18 or > 80 years;
Unable to give written informed consent;
Pregnancy/lactation;
Extreme obesity: BMI > 35;
Perceived difficult intubation.
Patients requiring a rapid sequence induction
Patients on beta‐blockers
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Response Index (continuous measurement allowing assessment).
- Secondary Outcome Measures
Name Time Method Cardiovascular parameters (HR, BP, PPG wave amplitude and non‐invasive CO measured<br>at 30 s intervals from the Nexfin® device)<br>Occurrence of purposeful movement of the patient.<br>BIS values.