Behandeling van endometriose met groene thee: Een dubbel blind gerandomiseerde placebo gecontroleerde pilot studie.
Recruiting
- Conditions
- EndometriosisEndometrioseEpigallocatechin gallate Epigallocatechine gallaatEGCGGreen teaGroene thee
- Registration Number
- NL-OMON20203
- Lead Sponsor
- VU university medical centerDepartment of Obstretics and Gynaecology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. Signed and dated informed consent;
2. The use of oral contraceptives;
Exclusion Criteria
1. Previous/ current use of hormonal agents including GnRH agonists (not within 6 cycles), progestins (not within 3 cycles), hormonal contraception (not within 1 cycle), IUD (mirena), specific oral contraceptives (Diane 35 and three phase oral contraceptives, not within one cycle);
2. Positive pregnancy test;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To evaluate if the VAS pain scores are lower in patients using EGCG versus placebo treatment;<br /><br>2. To evaluate if serum Ca-125 level is lower in patients using EGCG versus placebo treatment;<br /><br>3. To investigate if the total dosage of rescue pain medication is lower in patients using EGCG versus placebo treatment.
- Secondary Outcome Measures
Name Time Method 1. To investigate if the Biberoglu & Behrman severity profile is lower in patients using EGCG versus placebo treatment;<br /><br>2. To investigate if the menstrual bloodloss is lower in patients using EGCG versus placebo treatment.