Prevalence of Oral Findings in Adult Patients With Chronic Kidney Disease '' Cross Sectional 2 "
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 225
- 主要终点
- Oral mucosal lesions
研究概览
简要总结
The patients with chronic kidney disease suffer from many oral problems affecting the quality of life. The aim of our study is to assess their oral health to provide the proper management and increase their awareness
详细描述
The study will be held in the Nephrology units at the Kasr Al-Ainy Cairo university hospital.
The data collected through the questionnaire will be obtained through an interview between the investigator and the patient. Clinical examination will be performed for both oral (soft tissue) and dental (hard) tissue. For patients undergoing dialysis, examination will be performed before dialysis therapy Selection bias: will be minimized by enrolling the participants in the study in a consecutive order of the entering the clinic.
Non-respondent bias: will be minimized by explaining to the participants the aim of the study and their importance and role in the study.
Incomplete records: will be excluded from statistical analysis with reporting the cause of not completing the record.
Using a precision of 5, a design effect set at 1 with 90% CI (confidence interval), a total sample size of 250 pre-dialysis patients and 200 end stage renal disease patients will be sufficient. The sample size was calculated by Epi info software.The sample will be divided between two researchers; each researcher will have 50% of the whole sample to collect
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients >18 years old with a diagnosis of non-dialysis chronic kidney disease at stage 2, 3 and
- •Adult patients >18 years old with a diagnosis of end stage renal disease "stage 5".
- •Recorded data of Glomerular Filtration Rate for every patient.
- •Recorded data for dialysis patients (HCV, platelets count, creatinine, blood urea nitrogen, urea level and partial thromboplastin time).
排除标准
- •Adult patients <18 years.
- •End stage renal disease undergoing peritoneal dialysis.
- •Patients not physically able to participate in oral examination.
- •Patients with kidney transplantation.
- •Patients undergoing renal dialysis for reasons other than chronic kidney disease, such as acute renal failure, accidents, trauma, snake poisoning
结局指标
主要结局
Oral mucosal lesions
时间窗: 15 minutes
Clinical examination according to WHO guidelines
次要结局
- Periodontal condition(10 minutes)
- Hepatitis C Virus at dialysis stage(10 minutes)
研究者
Maryam Ahmed Essam Abdel Salam
BDS internal resident at oral medicine department
Cairo University