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Effect of vitamin D in major depressio

Phase 3
Conditions
Major depressive disorder.
Major depression
Registration Number
IRCT201201072394N6
Lead Sponsor
Vice-chancellor for research, Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Willing to participate;
Clinical diagnosis of major depressive disorder;
A score =15 in the 17-item Hamilton Depression Rating Scale;
Age 18 – 65 years;
Good health status based on medical history;
No antidepressant or dietary supplement use during the previous two months.
Exclusion criteria:
Substance abuse;
Pregnancy and lactation.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Depression severity. Timepoint: At baseline, weeks 2, 4, 6, 8. Method of measurement: Hamilton Depression Rating Scale.
Secondary Outcome Measures
NameTimeMethod
C-reactive protein. Timepoint: At baseline, after weeks 2, 4, 6, 8. Method of measurement: ELISA.;Total antioxidant capacity. Timepoint: 8 weeks. Method of measurement: FRAP.;IL-6. Timepoint: At baseline, after weeks 2, 4, 6, 8. Method of measurement: ELISA.
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