Effect of naltrexone in chronic urticaria
Not Applicable
- Conditions
- rticaria.Urticaria
- Registration Number
- IRCT20210407050878N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
Diagnosis of chronic urticaria based on clinical criteria
Lack of response to standard treatment
Patients of both males and females
Age over 12 years
Exclusion Criteria
Pregnancy
Breast feeding
Allergy to naltrexone
Substance abuse
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Itching Score based on UAS7 (Urticaria Activity Score7). Timepoint: Itching score based on UAS7 (Urticaria Activity Score7): During the week before beginning intervention, during the second week of intervention, during the fourth week of intervention. Method of measurement: Based on UAS7 (Urticaria Activity Score7).;Urticaria Score based on UAS7 (Urticaria Activity Score7). Timepoint: Urticaria score based on UAS7 (Urticaria Activity Score7): during the week before beginning intervention, during the second week of intervention, during the fourth week of intervention. Method of measurement: Based on UAS7 (Urticaria Activity Score7).
- Secondary Outcome Measures
Name Time Method Itching score based on VAS (Visual Analogue Scale). Timepoint: Before intervention, end of the second week of intervention, end of the fourth week of intervention. Method of measurement: Based on VAS (Visual Analogue Scale).;Quality of life based on DLQI (Dermatologic Life Quality Index). Timepoint: Before intervention, end of the second week of intervention, end of the fourth week of intervention. Method of measurement: Based on DLQI (Dermatologic Life Quality Index).