Immunomodulatory effects of a mixed Chinese herbal formula on perennial allergic rhinitis patients with high IgE levels via regulatory B cells

Taoyuan Chang Gung Memorial Hospital0 个研究点目标入组 49 人开始时间: 2023年6月7日最近更新: 2023年6月20日

适应症

试验速览

暂无简介。

•1. A clinical history of perennial allergic rhinitis characterized by rhinorrhea, sneezing, nasal itching, or nasal obstruction, occurring for an hour or more on most days throughout the year
•2. Hypersensitivity to dust mite allergens or other common allergens, as confirmed using a multiple allergen simultaneous test in the high total serum IgE levels (= 200 IU/mL) group
•3. Male and female patients aged 20 to 65 years
•4. Willing to take medicine as scheduled in this study
•5. Volunteered for study enrollment and signed informed consent

•1. Diagnosed as active infectious diseases, such as acute sinusitis, pneumonia, or bronchitis
•2. Severe organ dysfunction, such as impaired renal and hepatic function at initial diagnosis (including chronic kidney disease stages III, IV, and V and AST, ALT = 3 × the upper normal limit), liver cirrhosis, or heart failure
•3. Using antihistamine, steroid, leukotriene inhibitors, immunosuppressant, or other Chinese herbal medicine for 1 month before enrollment
•4. Women who are pregnant or are planning to conceive

发起方

Taoyuan Chang Gung Memorial Hospital