MedPath

Clareon PanOptix Pro vs. Clareon PanOptix - Study B

Not Applicable
Completed
Conditions
Aphakia
Presbyopia
Registration Number
NCT06401551
Lead Sponsor
Alcon Research
Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.

Detailed Description

Subjects will attend 9 scheduled study visits for a total individual duration of participation of approximately 7 months. The primary endpoint will be assessed at the Month 2 follow-up visit. Both eyes of a subject must qualify for enrollment into this study.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
161
Inclusion Criteria
  • Understand and sign an ethics committee-approved informed consent form;
  • Willing and able to attend all scheduled study visits as required by the protocol;
  • Planned cataract surgery (both eyes);
  • Preoperative corneal astigmatism less that 1.00 diopter in each eye.
  • Other protocol-defined inclusion criteria may apply.

Key

Exclusion Criteria
  • Women of childbearing potential if currently pregnant, intend to become pregnant during the study, or are breastfeeding;
  • Ocular conditions as specified in the protocol;
  • Subjects who desire monovision correction.
  • Other protocol-defined exclusion criteria may apply.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Mean Monocular Photopic Best Corrected Distance Visual Acuity (BCDVA)Month 2 postoperative

Visual Acuity (VA) will be assessed for each eye individually using Early Treatment Diabetic Retinopathy Study (ETDRS) reading charts at a distance of 4 meters from the subject under photopic (well-lit) conditions with correction in place. BCDVA will be measured in logarithm Minimum Angle of Resolution (logMAR). LogMAR values typically range from -0.3 (20/10 vision on the Snellen chart) to 1 (20/200 vision), with lower scores indicating better vision.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (8)

Wolstan & Goldberg Eye Associates

🇺🇸

Torrance, California, United States

Grosinger, Spigelman & Grey Eye Surgeons, P.C.

🇺🇸

Bloomfield Hills, Michigan, United States

Moyes Eye Center

🇺🇸

Kansas City, Missouri, United States

Cincinnati Eye Institute

🇺🇸

Cincinnati, Ohio, United States

Carolina Eye Care Physicians

🇺🇸

Charleston, South Carolina, United States

Vision for Life

🇺🇸

Nashville, Tennessee, United States

Houston Eye Associates

🇺🇸

Houston, Texas, United States

The Eye Institute of Utah

🇺🇸

Salt Lake City, Utah, United States

Wolstan & Goldberg Eye Associates
🇺🇸Torrance, California, United States

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