Individualized Intraoperative PEEP Following Alveolar Recruitment Maneuvres and Postoperative Respiratory Complications
- Conditions
- Postoperative Respiratory Complications
- Registration Number
- NCT06600386
- Lead Sponsor
- Asklepieion Voulas General Hospital
- Brief Summary
Patients ASA I-III, undergoing laparoscopic abdominal surgery will be randomly assigned, into one of two groups, namely group C-PEEP , that will be the control group ; and group I-PEEP, where alveolar recruitment maneuvres will take place in order to identify each patient\'s individualized optimal PEEP. All patients will receive a standardized anesthesia regimen. The lung ultrasound score will be evaluated in all patients in the PACU and then respiratory complications will be recorded on the 24th hour, 48th hour, 7th day and 30the day, postoperatively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 69
ASA I-III Laparoscopic abdominal surgery
Severe kidney dysfunction Severe hepatic dysfunction Severe respiratory disease Severe cardiac disease Severe neuromuscular disease BMI>30 Severe intraoperative hemorrage Severe intraoperative hemodynamic instability
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Respiratory complications 30 days Postoperative complications (atelectasis, bronchospasm, pneumonia, respiratory failure, ARDS, prolonged mechanical ventilations, reintubation, pleural infusion, COPD exacerbation)
- Secondary Outcome Measures
Name Time Method Pplat intraoperatively SpO2 intraoperatively PCO2 intraoperatively PaO2/FiO2 intraoperatively Cdyn intraoperatively MAP intraoperatively Ppeak intraoperatively heart rate intraoperatively LUS score Preoperatively and 30 minutes postoperatively Ultrasonographic findigs
Trial Locations
- Locations (1)
Asklepieion Hospital of Voula
🇬🇷Athens, Attica, Greece
Asklepieion Hospital of Voula🇬🇷Athens, Attica, Greece