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临床试验/CTRI/2021/04/032933
CTRI/2021/04/032933尚未招募2 期

Comparative Clinical Study To Evalauate The Effect Of Trikatu Avapidana Nasya And Trikatu Taila Nasya On Nasal Mucosa In Vataja Pratishyaya (Allergic Rhinitis)

Department of Shalakya Tantra1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2021年4月26日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
1.Watery nasal discharge

研究概览

简要总结

AllergicRhinitis is an IgE mediated immunologic response of nasal mucosa to air borneallergens and is characterized by watery nasal discharge, nasal obstruction,sneezing and itching of nose, eyes, palate and pharynx. It is two types theyare seasonal and perennial.It is better considered as a unifiedallergic airway, or even a systematic disease- with inflammatory changes incirculation and bone marrow. More than 10million people areaffected by allergic rhinitis in India irrespective of age group. Ithas negative impact on the quality of life.  Allergic Rhinitis may be compared with VatajaPratishyaya, characterized by watery nasal discharge, nasal blockage,difficulty in breathing, dryness of throat, palate, lips along with prickingtype of pain in temporal region and change in voiceand sneezing.

Allopathic Treatment involves oral administrationof anti-histamine, alpha-adrenergic and corticosteroid drugs, which have sideeffects like drowsiness, rhinitis medicamentosa and mucosal atrophy respectively,other treatment modalities includes avoidance of allergen and immunotherapy. Immunotherapy shows no clinical improvement after prolonged usage.

In VatajaPratishyaya treatmentprotocol of Ardita, Vataja Kasa, and Pinasa are advocated.It includes *Sneha Dhuma, Swedana, Upanaha, Anutaila Nasya , AvapidanaNasya, Pradhamana Nasya, Asthapana Basti.*Intakeof Ghrita , Maricha with Guda, and Vyoshadi Vati.

Since, both Taila and AvapidanaNasyaare advocated in management of Vataja Pratishyaya, this study is aimedto compare the effect of Trikatu Taila and Trikatu Avapidana Nasyaon nasal mucosa in the management of Vataja Pratishyaya.

研究设计

研究类型
Interventional
分配方式
Random Number Table
盲法
Open Label

入排标准

年龄范围
7.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients having signs and symptoms of allergic rhinitis(Vataja Pratishyaya) 2.Irrespective of their gender, socio-economic status, educational status and religion.
  • 3.Age group between 7 to 60 years.

排除标准

  • 1.Patients unfit for Nasya.
  • 2.Patients suffering from nasal polyposis, nasal carcinoma, epistaxis.

结局指标

主要结局

1.Watery nasal discharge

时间窗: 7 days

2.Nasal obstruction

时间窗: 7 days

3.Sneezing

时间窗: 7 days

REDUCTION in

时间窗: 7 days

次要结局

  • Complete absence in(1.Watery nasal discharge)

研究者

发起方
Department of Shalakya Tantra
申办方类型
Research institution and hospital

研究点 (1)

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