Standard Oxytocin Versus High Dose Oxytocin to Control Postpartum Hemorrhage in High Risk Pregnancy During Elective Cesarean Section
- Registration Number
- NCT06560099
- Lead Sponsor
- Ain Shams University
- Brief Summary
Controlling hemorrhage during and after a cesarean section reduces significantly maternal mortality and morbidity and the present study is important for detection of the effectiveness of routinely increasing the oxytocin dose instead of using the standard dose only in preventing postpartum hemorrhage and additional use of uterotonics in the first 24 hours after cesarean section for high risk pregnancy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Female
- Target Recruitment
- 39
Inclusion Criteria
-
- Medical disorders ie: Hypertensive diseases with pregnancy - Diabetes Mellitus - Collagen diseases - Coagulopathies - Cardiac diseases - Anemia
- History of postpartum hemorrhage
- Placental disorders ie: placenta previa
- Infertility and ICSI
- High Parity
- History of Endometriosis
- Fetal disorders (IUGR, IUFD, Preterm, Congenital anomalies, oligohydramnios or polyhydramnios, macrosomia)
- Preterm labor on uterine relaxants
- Twins pregnancy
- Patients on antiplatelets and anticoagulants
- Uneventful antenatal care
Exclusion Criteria
-
- Oxytocin Allergy
- Normal uncomplicated pregnancy
- Emergency cesarean section
- Exhausted uterus due to trial of normal labor
- Couvelaire uterus
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group A (standard oxytocin dose) Oxytocin - Group B (high dose oxytocin) Oxytocin -
- Primary Outcome Measures
Name Time Method blood loss at the end of the operation measure blood in suction, towels and pads
- Secondary Outcome Measures
Name Time Method haemoglobin 6 hours postoperative by laboratory asessment