Comparison of the effect of local cold and warmth upon the size of bruising at the injection site of subcutaneous Enoxaparin.

Phase 2

• Conditions: Diseases of skin and subcutaneouse tissue.; L00-L99

• Registration Number: IRCT2014040917197N1
• Lead Sponsor: Tehran Universiy of Medical Sciences

Brief Summary

Purpose: This study aimed to assess the effect of the application of local cold and cold-hot packs upon the size of bruising at the injection site of subcutaneous Enoxaparin sodium. <br /> Methods: One-hundred and eighty patients with coronary diseases were allocated randomly to three groups: (i) local cold gel pack group; (ii) local cold-hot gel pack group; and (iii) control group. Assessment of the presence of a bruise was conducted at 24, 48 and 72 hours after the injections for all patients. <br /> Results: The cold-hot pack group had significantly less and smaller injection site bruising than the two other groups at 48 and 72 hours (both p < 0.001). <br /> Conclusions: The local application of cold-hot packs is more effective on reducing bruises following enoxaparin sodium injections when compared with local cold pack application alone. Thus, this process can improve the quality of nursing care for hospitalized patients receiving these injections.<br /> Keywords: low-molecular-weight heparin; enoxaparin; injections; bruising; cold application<br />

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

The patient do not be pregnant; has not any coagulation disorders; the patient has the written order for injection Enoxaparin 60mg by doctor per 12 hours; and there is not record of previous injections during last 24hours in his/her abdominal area.
Exclusion criteria: The drug of Enoxaparin stopped by doctor or changed; there is bleeding in injection area.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The size of bruising at the injection site of subcutaneous Enoxaparin. Timepoint: Until 3 days after the injection. Method of measurement: Using a plastic ruler.