Stopping Cardiovascular Treatments and Mortality in a MICU

• Conditions: Critical Care; Cardiovascular Diseases; Medication; Outcome, Fatal

• Registration Number: NCT04121429
• Lead Sponsor: University Hospital, Brest

Brief Summary

Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified. The question of the study is to investigate wether such treatment interruption might be responsible for prognosis modifications.

Detailed Description

Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified.

Few studies have investigated the outcome impact of medications interruption and/or modifications following hospital admission. We did consider that it might be interesting to study whether treatment continuation, interruption, and/or re-introduction following ICU admission may modify patients' outcome either in the ICU or following hospital discharge (at 3,6 and 12 months).

Study Timeline

• Status Verified: 2019-04
• Study Start: 2019-05-02
• Study First Submitted: 2019-10-04
• Study First Submitted QC: 2019-10-08
• Last Update Submitted: 2019-10-08
• Study First Posted: 2019-10-09
• Last Update Posted: 2019-10-09
• Primary Completion: 2019-11-02
• Study Completion: 2019-11-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• All patients with cardiovascular treatment prior to ICU admission

Exclusion Criteria

• Data unavailability
• Consent withdrawal following information

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICU Mortality	2 months following ICU Discharge	Patients mortality will be assessed at the end of the ICU stay (two months)

Secondary Outcome Measures

Name	Time	Method
Mortality at Month 3 following discharge	3-months following discharge
Hospital mortality	2 months following Hospital Discharge	Patients mortality will be assessed at the end of the hospitalisation stay (two months)
Mortality at Month 6 following discharge	6-months following discharge
Mortality at Month 12 (1-year) following discharge	12-months following discharge

Trial Locations

Locations (1)

Medical Intensive Care Unit, Brest University Hospital; 🇫🇷 Brest, France