A Comparative Pharmaceutico-Analytical Study of Two Different Formulations of Chitraka Ghrita and Their Clinical Evaluation w. s. r to Agnimandya
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Improvement in Agnimandya assessed through following parameters: Abhyavahare Abhilasha, Ruchi Ahara Kale, Ahara Pramana, Ahara Jarana Kala, Jeerna Ahara Lakshana (Jarana Shakti), Utsaha, and Bala. by giving scores before and after treatment.
研究概览
简要总结
This is a prospective, randomized, comparative pharmaceutico-analytical and clinical study designed to evaluate two formulations of Chitraka Ghrita in the management of Agnimandya.
The first formulation uses Ghrita prepared through a classical method involving Chitraka-moola-lepita vessel as referenced in Chakradatta, while the second uses conventionally prepared Ghrita without the lepita step.
The study aims to assess whether the classical pharmaceutical method, which is more time-consuming and effort-intensive, provides superior clinical efficacy to justify its use.
Both formulations will be analyzed for their physicochemical properties.
A total of 30 patients diagnosed with Mandagni will be selected and randomly divided into two groups.
Clinical efficacy will be assessed using structured Ayurvedic parameters including Abhyavahare Abhilasha, Ruchi Ahara Kale, Ahara Pramana, Ahara Jarana Kala, Jeerna Ahara Lakshana (Jarana Shakti), Utsaha, and Bala, evaluated before and after intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients with lakshanas of Mandagni as mentioned in classics, H/O symptoms within 3 months, Persisting symptoms more than 3 days.
排除标准
- •Age less than 16 years and more than 60 years, Preganacy and Lactation, Severe Renal/Hepatic/Cardiac disease, Patients with psychic disorders, Patients diagnosed with any structural disease of GIT, Agnimandya as a symptom of other disease.
结局指标
主要结局
Improvement in Agnimandya assessed through following parameters: Abhyavahare Abhilasha, Ruchi Ahara Kale, Ahara Pramana, Ahara Jarana Kala, Jeerna Ahara Lakshana (Jarana Shakti), Utsaha, and Bala. by giving scores before and after treatment.
时间窗: Day 0 (Before treatment), Day 7 (After treatment), Day 10 (Follow-up)
次要结局
- Comparison of clinical response between two formulations of Chitraka Ghrita in Mandagni based on Ayurvedic parameters(Day 7 (end of drug administration), Day 10 (follow-up))
研究者
Dr Adithya Narayana Bhat
KVG Ayurveda Medical college and hospital