The NEMO Project: Longitudinal Monitoring of Neuropsychological Outcomes in Pediatric Oncology

Recruiting

Conditions: europsychologische problemen als gevolg van (de behandeling van) kinderkanker
cognitieve problemen
Neuropsychologische beperkingen

Registration Number: NL-OMON52025

Lead Sponsor: Prinses Máxima Centrum voor Kinderoncologie

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 168

Inclusion Criteria

• New primary diagnosis of brain tumor, other solid tumor, or
hemato-oncological condition
• Age between 6 and 18 years old at diagnosis
• Primarily followed at the Princess Maxima Center for oncological care

Exclusion Criteria

• No signed informed consent
• Insufficient knowledge of the Dutch language to perform the
neuropsychological assessment or complete questionnaires
• Significant visual, motor, or developmental problems and thus alternative
neuropsychological assessments would be needed (i.e., blindness, deafness,
profound developmental delay)
• Patients receiving palliative therapy or end-of-life care
• Treating physician or psychologist advises against inclusion

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Age-standardized performance on functional outcome measures (intelligence,<br /><br>memory, academics, adaptive functioning, social-emotional functioning) and<br /><br>broader aspects of neuropsychological functioning (attention, executive<br /><br>function, working memory, processing speed, visual-spatial/motor, quality of<br /><br>life). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>(1) Latent longitudinal trajectories in performance on brief monitoring<br /><br>measures and their relationship with functional outcome measures, in other<br /><br>words, differences in functional outcome measures between groups with different<br /><br>cognitive trajectories. (2) The (strength of the) relationship between medical<br /><br>(e.g. pre-term birth, pre-morbid diagnoses, treatment) and psychosocial (e.g.<br /><br>socioeconomic status) risk factors and functional outcome measures. (4)<br /><br>Acceptability and feasibility of a monitoring program.</p><br>