Infant kidney dialysis and filtration: the I-KID study

Not Applicable

Completed

• Conditions: Acute renal insufficiency or fluid overload; Urological and Genital Diseases; Renal and Urogenital/ Renal failure

• Registration Number: ISRCTN13787486
• Lead Sponsor: The Newcastle Upon Tyne Hospitals NHS Foundation Trust

Brief Summary

2023 Results article in https://dx.doi.org/10.1097/PCC.0000000000003220 (added 13/03/2023) 2021 Protocol article in https://doi.org/10.1136/bmjpo-2021-001224 (added 19/01/2024) 2024 Results article in https://doi.org/10.3310/VGJT3714 (added 19/01/2024)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-06-28
• Study Completion: 2022-02-28
• Last Update Posted: 29 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

Current inclusion criteria as of 25/09/2019:
1. Patients in PICU with a body weight of 0.8-7.99 kg who require continuous RRT for acute renal insufficiency or fluid overload as part of their standard clinical care
2. Person with legal parental responsibility (PR) for the patient has provides written informed consent for the patient to take part in the study. This may be after the patient has started dialysis in an emergency situation to not delay any treatment.

Previous inclusion criteria:
1. Patients in PICU with a body weight of 0.8 kg – 7.99 kg who require continuous RRT for acute renal insufficiency or fluid overload as part of their standard clinical care
2. Person with legal parental responsibility (PR) for the patient has provided written informed consent for the patient to take part in the study

Exclusion Criteria

1. Patient with known chronic renal failure already on adequate RRT
2. Patient already established on adequate RRT for whom entry into the study would require additional central venous access, if that access is not clinically indicated
3. Patient has an underlying metabolic diagnosis, including hyper ammonaemia
4. Clinician makes a clinical decision that the patient should not receive RRT using NIDUS
5. Unable to receive written informed consent for data collection from a person with legal PR for the patient

Study & Design

• Study Type: Interventional
• Study Design: Not specified