Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage
- Conditions
- Cerebral VasospasmSubarachnoid HemorrhageCerebral Aneurysm
- Registration Number
- NCT00962546
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
Cerebral vasospasm is a devastating complication of subarachnoid hemorrhage after cerebral aneurysm rupture leading to cerebral ischemia and potentially cerebral infarction. The current gold standard diagnostic imaging study for cerebral vasospasm is catheter cerebral angiography, an invasive diagnostic procedure carrying a complication rate of 1-2% per procedure. Computed tomographic perfusion imaging (CTP) and computed tomographic angiography (CTA) are noninvasive diagnostic imaging studies frequently utilized in the evaluation of embolic and thrombotic cerebral infarct. The investigators hypothesize that CTP and CTA may be utilized as screening tools for cerebral vasospasm following aneurysmal subarachnoid hemorrhage requiring treatment and provide prognostic information.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 4
- subarachnoid hemorrhage after aneurysm rupture
- renal insufficiency
- pregnancy
- contrast reaction
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CT perfusion parameters at time of catheter angiogram
- Secondary Outcome Measures
Name Time Method Disposition at discharge At time of hospital discharge vessel narrowing by CT angiography at time of catheter angiogram
Trial Locations
- Locations (1)
Barnes-Jewish Hospital
🇺🇸St. Louis, Missouri, United States