Does the Harmonic Scalpel Reduce Blood Loss and OR Time in Major Head and Neck Cancer Surgery Undergoing Major Surgery for Oral Cavity Squamous Cell Carcinoma?
Not Applicable
Completed
- Conditions
- Oral Cavity Squamous Cell Carcinoma, Treated With Surgery
- Interventions
- Procedure: surgical resection
- Registration Number
- NCT02017834
- Lead Sponsor
- University of Calgary
- Brief Summary
The harmonic scalpel is a tool that may reduce operative blood loss. Some studies also indicate it may result in faster surgery. A recently published randomized study from our group shows the harmonic scalpel reduces blood loss in neck dissection but it did not offer any reduction in OR time. The present study investigates the utility of the harmonic scalpel in resections involving removal of oral cavity tissues as well as the neck. Oral cavity resections are especially prone to blood loss and we believe the harmonic scalpel will confer benefits in this type of surgery, potentially reducing the need for blood transfusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- age > 18 years
- oral cavity scc
- primary surgery including either uni or bilateral neck dissection (levels I-IV)
Exclusion Criteria
- previous treatment for head and neck cancer
- unable or unwilling to give informed consent
- history of bleeding disorder
- other contraindications to surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description standard technique surgical resection - harmonic scalpel surgical resection -
- Primary Outcome Measures
Name Time Method blood loss intraoperative
- Secondary Outcome Measures
Name Time Method operating time intraoperative
Trial Locations
- Locations (1)
Foothills Hospital
🇨🇦Calgary, Alberta, Canada