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Clinical Trials/NCT00122291
NCT00122291
Unknown
Phase 2

A Phase 2 Study of Preoperative Radiation Therapy and Capecitabine (an Oral Fluoropyrimidine Carbamate) in Locally Advanced Rectal Cancer

Alberta Health services1 site in 1 country66 target enrollmentJanuary 2002
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ConditionsRectal CancerNeoplasm Metastasis
DrugsCapecitabine

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Rectal Cancer
Sponsor
Alberta Health services
Enrollment
66
Locations
1
Primary Endpoint
safety
Last Updated
14 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this trial is to study the efficacy of preoperative radiation therapy and capecitabine in locally advanced rectal cancer.

Detailed Description

The purpose of this trial is to study the efficacy of preoperative radiation therapy and capecitabine in locally advanced rectal cancer.

Registry
clinicaltrials.gov
Start Date
January 2002
End Date
TBD
Last Updated
14 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Biopsy - proven rectal cancer
  • •Transmural rectal wall invasion
  • •Karnofsky performance status \>70
  • •Normal bone marrow, liver and kidney function

Exclusion Criteria

  • •Distant metastases
  • •Prior pelvic radiation
  • •Inflammatory bowel disease
  • •Severe ischemic heart disease
  • •Anticoagulant therapy
  • •Pregnancy

Outcomes

Primary Outcomes

safety

response

Study Sites (1)

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