Clinical trial to evaluate the safety and feasibility of online adaptive radiotherapy using cone-beam CT for pancreatic cancer
Phase 1
Recruiting
- Conditions
- pancreatic cancerC535836
- Registration Number
- JPRN-jRCT1051230087
- Lead Sponsor
- Mizowaki Takashi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
1. Confirmed pancreatic adenocarcinoma by endoscopic ultrasound-fine needle aspiration.
2. Patients with borderline resectable pancreatic cancer or locally advance pancreatic cancer.
3. Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Exclusion Criteria
1. Patients who have received radiotherapy to upper abdomen.
2. Tumor with direct invasion to stomach, duodenum, or small intestine.
3. Patients who cannot be treated expiratory breath-hold technique.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acute Grade 3 or higher adverse event non-incident rate which gastrointestinal origin
- Secondary Outcome Measures
Name Time Method Completion probability of treatment protocol, Adverse event rate except for gastrointestinal origin, Treatment time, Intra-fractional motion of organ, Inter-fractional motion of organ, Dosimetric parameters in adaptive and non-adaptive plan, The contour difference between in treatment and after treatment, The contour difference between operators, The optimal margin of organ at risk in oART