Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,146
- 试验地点
- 1
- 主要终点
- Proportion anti-SARS-CoV2 seropositive
研究概览
简要总结
In mid-February 2020, within the Oise (France) cluster, a case of COVID-19 disease caused by a SARS-CoV2 infection was described among the personnel of the Creail Air Force Base (BA110). This resulted in the beginning of an epidemic controlled by epidemiological measures. One month later, containment measures were taken at the national level, measures that also applied to BA110 personnel. These personnel, exposed to both the initial phase of the epidemic and national protection measures, represent an extremely interesting population for understanding the epidemiological dynamics of the virus, particularly at a time when France is lifting the containment measures. It becomes extremely important to understand the levers of viral spread in order to adjust the health measures to be maintained as best as possible.
The main objective of this study is to determine the extent of virus diffusion in this highly circulating population, as evidenced by several identified cases of COVID-19.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Active military or civilian defence personnel working on the Creil Air Force Base (BA110) during the period of interest (from February 1st 2020 to the end of the study)
排除标准
- •Contraindication to blood sampling
- •Pregnant, parturient, breastfeeding woman
结局指标
主要结局
Proportion anti-SARS-CoV2 seropositive
时间窗: Day 0
The percentage of the study population with positive serological status will be determined. ELISA serology test will be used to detect anti-SARS-CoV2 antibodies (IgG and IgM) at Day 0
次要结局
- Change of antibody level over time(3 months and 9 months after Day 0)
- Proportion of asymptomatic anti-SARS-CoV2 seropositive participants(Day 0)
- Agreement between the anti-SARS-CoV2 serological results obtained using two different techniques (detecting the presence of different antibodies)(Day 0)
- Proportion of serum neutralization positive(Day 0)