ACTRN12620001122943尚未招募未知
Reducing time to appropriate antibiotics by integrating rapid pathogen genome sequencing with personalised antimicrobial dosing in children and adults with sepsis. A study protocol for a prospective, multi-centre trial (DIRECT)
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Diagnosis
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 1 Months 至 o limit（—）
- 性别
- All
入选标准
- •1.Admitted to paediatric or adult ICU at one of the participating centres
- •2.Decision to treat for suspected sepsis, defined as suspected or proven infection with suspected or proven organ dysfunction.
- •3.Commenced within 24h on intravenous broad-spectrum antibiotics, or within 24h of a change to new antibiotics consistent with treatment for a new episode of suspected sepsis.
- •4.Blood cultures are being obtained or were obtained within the past 12 hours
排除标准
- •1.Inability to gain informed consent during the study period
- •2.Neonates
- •3.Death is likely imminent
- •4.Palliative care patient
研究者
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