Prospective Randomized Controlled Study on Arthroscopic Treatment Combine With TXA for Elbow Stiffness
Overview
- Phase
- Not Applicable
- Intervention
- TXA
- Conditions
- Tranexamic Acid
- Sponsor
- Beijing Jishuitan Hospital
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Mayo Elbow Performance Score
- Last Updated
- 4 years ago
Overview
Brief Summary
This study is a prospective randomized controlled study of different arthroscopic treatments for elbow stiffness combined with tranexamic acid(TXA) injection. The patients with stiffness were randomly divided into groups before the operation. After the arthroscopic operation was completed, they were divided into a local TXA injection group and a control group (normal saline) to perform additional operations for reduction of hemorrhage. In different time periods, the quantitative and qualitative indicators including pain, functional score, range of motion, level of Hemoglobin, the circumference of the limb 10cm above and below the elbow, amount of hemorrhage, etc. were compared between groups at the same time period to evaluate the difference in the effect of arthroscopic treatment combined with TXA on the treatment of reduction of hemorrhage. Determine the effectiveness of TXA.
Investigators
Yi Lu
Director of Sports Medicine Service of Beijing Jishuitan hospital
Beijing Jishuitan Hospital
Eligibility Criteria
Inclusion Criteria
- •Clinically diagnosed patients with elbow stiffness Young and middle-aged patients aged 18 to 60 with failed nonoperated treatment Voluntarily accept randomized controlled grouping, cooperate with treatment and follow up patients No other comorbidities or medical diseases affect the surgical patients -
Exclusion Criteria
- •Elderly people older than 60 years old and patients younger than 18 years old With severe comorbidities or medical diseases affect the surgical patients
Arms & Interventions
Study group
Arthroscopic treatment with TXA injection
Intervention: TXA
Control group
Arthroscopic treatment with normal saline injection
Intervention: Saline
Outcomes
Primary Outcomes
Mayo Elbow Performance Score
Time Frame: baseline-6 months postoperatively
A score used to evaluated the elbow function
Secondary Outcomes
- Visual analogue scale(baseline-6 months postoperatively)
- Circumference of upper extremity(baseline-6 months postoperatively)
- change of hemoglobin(baseline-6 months postoperatively)
- range of motion(baseline-6 months postoperatively)