Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for early breast cancer (HOT) - HOT

Prof John Yarnold, Institute of Cancer Research0 sites63 target enrollmentFebruary 23, 2005

Overview

No summary available.

Registry

who.int

Start Date

February 23, 2005

End Date

December 31, 2008

Last Updated

6 years ago

Study Type

Interventional clinical trial of medicinal product

Sponsor

Prof John Yarnold, Institute of Cancer Research

•Past history of surgery and radiotherapy for early breast cancer including radiotherapy to the axilla and/or SCF at least 24 months prior to trial entry. Arm lymphoedema (at least 15% increase in arm volume). No evidence of cancer recurrence. Physical and psychological fitness for hyperbaric oxygen therapy. Written informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range
•F.1\.3 Elderly (\>\=65 years) yes
•F.1\.3\.1 Number of subjects for this age range

•Prior hyperbaric oxygen therapy, claustrophobia, epilepsy. Chronic obstructive airways disease, bullous lung disease, acute or chronic pulmonary infection, uncontrolled asthma, untreated phneumothorax. Previous ear operations, eustachian tube dysfunction or recurrent attacks of vertigo.