ISRCTN56112439已完成未知
The effects of add-on corticosteroids on renal outcomes in patients with biopsy-proven HIV-associated nephropathy: a single centre study from South Africa
GROOTE SCHUUR HOSPITAL/ UNIVERSITY OF CAPE TOW0 个研究点目标入组 40 人开始时间: 2018年9月5日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/30728003
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Histologically-proven HIV-associated nephropathy, defined as having the presence of chronic tubulointerstitial inflammation with plasma cells, lymphocytes and microcysts, along with any of the following:
- •1.1. Collapsing glomerulopathy
- •1.2. Focal segmental glomerulosclerosis
- •1.3. Podocyte hypertrophy and/or hyperplasia
- •2. Antiretroviral therapy naïve for at least 2 weeks prior to renal biopsy
- •3. Initiation of antiretroviral therapy within 1 month of the renal biopsy
- •3. Aged 18 years or older
- •4. Able to provide written informed consent
排除标准
- •1. Any active infection
- •2. Kaposi sarcoma
- •3. Active cytomegalovirus
- •4. Inability to follow-up at study centre
研究者
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