Acute Candesartan Cilexetil Outcomes Stroke Trial

City Hospitals Sunderland NHS Foundation Trust (UK)0 个研究点目标入组 50 人开始时间: 2005年9月14日最近更新: 2019年10月29日

适应症

试验速览

暂无简介。

•1. Clinical diagnosis of acute ischaemic stroke within 72 hours of symptom onset (proven on CT imaging).
•2. Medically stable with no evidence of acute infection and not receiving antibiotic therapy.
•3. Neurologically stable with no progression on NIHSS.
•4. Able to swallow safely and able to tolerate unthickened oral fluids without risk of aspiration.
•5. Mean blood pressure in the unaffected arm >120/70 from three readings taken within one hour at twenty minute intervals using a calibrated Omron M5-1 BP monitor.

•1. Previous severe disability (Modified Rankin Score greater to or equal to 3).
•2. Nursing home resident.
•3. Previous history of congestive cardiad failure requiring treatment with an ACE inhibitor or Angiotensin Receptor Blocker (ARB).
•4. Renal impairment (defined serum creatinine >200 umol/l).
•5. Women of child bearing potential.
•6. Minors aged less than 18.
•7. History of evidence of dementia without capacity for consent.

发起方

City Hospitals Sunderland NHS Foundation Trust (UK)