Prospective cohort study to determine the association of pre-operative nutritional status with 90 days morbidity among patients undergoing Radical cystectomy for Muscle Invasive Bladder Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To correlate the preoperative nutritional status with the 90 days morbidity in patients undergoing radical cystectomy for muscle invasive bladder cancer.
研究概览
简要总结
Bladder cancer is among the top ten cancers in the world. Muscle invasive bladder cancer constitutes of approximately one-fourth of the total bladder cancers. Radical cystectomy which is the gold standard treatment for bladder cancer is associated with higher morbidity and mortality. Also nutritional status of patients is associated with post surgical recovery of patients. Most of the literature on association of pre-operative malnutrition and post radical cystectomy complications comes from retrospective studies. Therefore we intend to perform a prospective cohort study to assess the association of pre-operative nutritional status and 90 days morbidity in patients undergoing radical cystectomy.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Adult patients [age ≥ 18 years].
- •2.Planned for Radical cystectomy.
- •3.Patients who can read,write and understand English language.
- •4.Who give written informed consent.
排除标准
- •Patients unfit/unwilling for surgery.
结局指标
主要结局
To correlate the preoperative nutritional status with the 90 days morbidity in patients undergoing radical cystectomy for muscle invasive bladder cancer.
时间窗: pre-operative nutritional status recorded upto within one week prior to surgery and morbidity upto 90 days post surgery
次要结局
- 1.To assess the effect of the preoperative nutritional status on the peri-operative parameters - duration of surgery, estimated blood loss, amount of blood transfused.(During radical cystectomy.)
- 2.To assess the effect of the pre-operative nutritional status on the length of hospital stay, readmission rates and the day of ureteric stent removal.(From day of surgery upto 90 days post-operatively)
- 3.To determine the prevalence of pre-operative poor nutritional status among the patients undergoing radical cystectomy.(Once within one week prior to surgery)